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Viruses

Viruses have been around since life began but they are 'of life', they are not technically 'alive' because they cannot themselves reproduce. They are extremely small - about 70 microns in diametre - and until the invention of electron microscopes in the 1930's their existance had only been inferred. 

To create copies of themselves they need a host cell with the necessary reproductive mechanisms. Over the millennia viruses have evolved the necessary mechanisms to penetrate cells, much like spermatozoa, and inject their DNA or RNA and capture the host's replication mechanisms so that the infected cell begins manufacturing thousands of virion (virus particle) clones of the invader. These then capture other nearby cells in the host animal or plant; or in similar bacteria.  Huge numbers of infected cells are usually destroyed in the process, sometimes killing the plant or animal.

 

c0487121 cell infected with covid 19 coronavirus particles sem web

Coronavirus particles (yellow) on the surface of a dying cell (that produced them)
Niaid/National Institutes of Health/Science Photo Library (from 
https://www.newscientist.com)

 

But animals plants and bacteria have become familiar with this threat and have in turn evolved means of dealing with or living with viruses to the extent that some are exploited for the benefit of the host.

In turn viruses evolve new strategies to perpetuate their reproduction. Thus new viruses arise from time to time, sometimes jumping from one species to another when an opportunity arises.

Many animals, including humans, have an immune system that has a memory of harmful viruses and means of neutralising them. Thus, once the animal has been infected and survived, the chances of reinfection are reduced.  Vaccines work by presenting our immune system with a harmless sample that allows it to recognise a particular harmful virus.

Since I first wrote this article the World has suffered a new viral pandemic.  It is a novel corona virus for which we have no established immunity and there is no vaccine.  At the end of June 2020 the Covi-19 virus has already killed half a million people.

It is estimated that this virus will no longer find sufficient vulnerable hosts to spread further after infecting around 70% of the populations in which it is spreading.  It has a case fatality rate of just under 1%, that is, of those who catch it just under one in a hundred die.  

Quarantine restrictions are in place in many countries to protect relatively uninfected areas, with local measures to eliminate 'hot spots'.  But the majority of the world's population, in excess of five billion, are in countries in which it is presently spreading.

Unless a vaccine is available soon it seems inevitable that many millions more will be killed.  The economic consequences are also dire.

 

 

 

 

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Travel

Egypt, Syria and Jordan

 

 

 

In October 2010 we travelled to three countries in the Middle East: Egypt; Syria and Jordan. While in Egypt we took a Nile cruise, effectively an organised tour package complete with guide, but otherwise we travelled independently: by cab; rental car (in Jordan); bus; train and plane.

On the way there we had stopovers in London and Budapest to visit friends.

The impact on me was to reassert the depth, complexity and colour of this seminal part of our history and civilisation. In particular this is the cauldron in which Judaism, Christianity and Islam were created, together with much of our science, language and mathematics.

Read more: Egypt, Syria and Jordan

Fiction, Recollections & News

Electricity Shocks

 

 

 

I've always thought that would be a good headline. 

Now that I have your attention I have to report that Emily McKie, my daughter, is the author of a new e-book on Smart Grid technology in her sustainable cities series.

 

 

 

Read more: Electricity Shocks

Opinions and Philosophy

The reputation of nuclear power

 

 

One night of at the end of March in 1979 we went to a party in Queens.  Brenda, my first wife, is an artist and was painting and studying in New York.  Our friends included many of the younger artists working in New York at the time.  That day it had just been announced that there was a possible meltdown at a nuclear reactor at a place called a Three Mile Island , near Harrisburg Pennsylvania. 

I was amazed that some people at the party were excitedly imagining that the scenario in the just released film ‘The China Syndrome’  was about to be realised; and thousands of people would be killed. 

Read more: The reputation of nuclear power

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